A Review on Gene Involved in Cancer Development and Oncogenic Viruses

Oncogenic viruses are the viruses that cause cancers in their natural hosts or experimental animal systems which are thought to be causative agents of about 15-20% of cancers. They have been broadly classified into the DNA oncogenic viruses and RNA oncogenic viruses based on the nature of the nucleic acid contain within their virion. The oncogenic DNA and RNA viruses that have been identified both in animals and humans includes retroviruses, papillomaviruses, herpesviruses and other DNA viruses. Oncogenic viruses promote cellular transformation, prompt uncontrollable cell generation and lead to development of malignant tumors. Virtually all type of normal cells may undergo the changes that eventually create tumors. For better understanding of cancer, knowing the mechanisms through which cancers produced is important. Generally this paper gives highlight about some of the gens induced cancer and related oncogenic viruses.